Anonymous
Posted: Mon Aug 31, 2009 4:04 am Post subject: Can I mix these medication?
I take Sinemet CR, Requip, Jumex and supplementary vitamins containing Zinc, calcium, T3, T4, Dhea,copper,Ferriltin , Folic acid,Vit D daily. I have unusual frequent tiredness,facial stiffness and feel sick.
Are they interacted each other and have effect? Kindly enligthen
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Kathrynne Holden, MSJoined: 22 Jan 2007Posts: 94Location: www.nutritionucanlivewith.com
Posted: Mon Aug 31, 2009 9:39 am Post subject:
. Dear Friend, You do not describe your “sick” feeling. However, the PD medications (Sinemet, Requip, and Jumex) can all have the effect of causing nausea, particularly when you first start taking them – perhaps that is the effect you are having? If so, try taking them with food for a few weeks until your body has time to adapt to the new medications. If you have been taking them for some time and still feel nausea, then ask your neurologist to prescribe Lodosyn (carbidopa); it can help overcome the nausea. I don’t think your vitamin and mineral supplements are interacting with the medications to make you feel sick or tired. However, if you are taking an iron supplement, I would take it about two hours apart from Sinemet, because iron can block levodopa absorption. Fatigue and tiredness are very common among people with PD, and there are a number of possible causes that need to be discussed with your doctor: - anemia (iron-deficiency, pernicious, megaloblastic) – anemia is not uncommon in PD and definitely causes tiredness, fatigue, sometimes shortness of breath and dizziness - B vitamin deficiency (can result in another type of anemia) - low blood sugar (hypoglycemia) – can lead to fatigue, dizziness, heart palpitations - deficiency of coenzyme Q10 – when present, taking supplements of CoQ10 10 often gives more energy - malnutrition - depression - PD can have “ups and downs” and you might be experiencing a temporary “down” that affects your energy or increases fatigue - do you take your Sinemet about 30 minutes before meals, so as to optimize its absorption and anti-PD effects? Sometimes people forget about this, and this can make a difference. - waning energy at the same time each day – sometimes energy levels drop after lunch; the body’s energy is diverted to metabolizing the food eaten, and it can result in sleepiness or fatigue; could that be a possibility? Let me know if you have further questions. ._________________Best regards, Kathrynne Holden, MS -- For a Parkinson Tip of the Day visit: http://www.nutritionucanlivewith.com/
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Anonymous
Posted: Wed Sep 02, 2009 2:40 am Post subject:
My frequent unusual tiredness and "sick "feeling was caused by vitamins and mineral supplements interacting with parkinson's medications and the effect on each other. I use to take my vitamin, mineral supplements about half an hours after my parkinson medications. As the result they block levodopa absorption. Therefore I have frequent .masked face; lack of blinking and expression and look "sick" and unusual tiredness. I feel much better after I take supplements two hours after the parkinson medication.
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Kathrynne Holden, MSJoined: 22 Jan 2007Posts: 94Location: www.nutritionucanlivewith.com
Posted: Wed Sep 02, 2009 12:25 pm Post subject:
. Dear Friend, Thank you for taking time to tell us about the changes you made to help you feel better. If you were taking iron supplements and/or large amounts of vitamin B6 (25 mg or more, and for some people as little as 10-15 mg), they would be very likely to cause the tired and sick feelings and the PD symptoms such as masked face. I generally recommend that people take levodopa about 30-60 minutes before meals, and iron and B6 supplements with the meal, or else at bedtime, so that they do not interfere with levodopa absorption. But everyone is different, so If it works best to take them two hours after the medications, then you have been your own best doctor! ._________________Best regards, Kathrynne Holden, MS -- For a Parkinson Tip of the Day visit: http://www.nutritionucanlivewith.com/
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Anonymous
Posted: Fri Sep 04, 2009 4:58 am Post subject:
My supplement vitamins containing: Boron Chelate 1mg,copper chelate 5mg, manganese chelate 2mg, Selenium chelate 200mg, Sod 300mg, Curcumin 500mg, chromium chelate 200mg,magnesium 200mg, molyodeum chelate 50mg, Alphalipoic acid 100mg, VIt A 2000 I.U, Vit 2 30mg, Vit 5 30mg, Vit H 300mg, Vit D 2500 IU,Vit 3 1000mg, Vit 1 200mg,Vit B3 40mg,Vit 6 50mg,VIt B9 1200 mg,Vit C 1000mg,Vit E (mixed nature) 200 IU, calcium 3000mg,Q10 200mg, Vit 5 30mg, VIt 2 30mg,VIt A 2000 I.U,tyl cysteine 1200mg VIt H 300mg,L-Tyrosne 50mg ,
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Kathrynne Holden, MSJoined: 22 Jan 2007Posts: 94Location: www.nutritionucanlivewith.com
Posted: Sat Sep 05, 2009 8:34 am Post subject:
. Dear Friend, Unfortunately, we do not normally refer to vitamins by number alone (i.e. vit. 2, vit 5), nor am I certain to which vitamins you refer when you mention vit. H, or vit B9. However, of all the B vitamins, only vitamin B6 is known to affect levodopa absorption. If by “vit 6" you are referring to vitamin B6, 50 mg would be quite a large amount, certainly more than enough to block your levodopa. And that would mean that PD symptoms were not controlled, resulting in the tiredness and masked face you describe. Since taking the supplements two hours after a meal is working for you, that should be fine. My personal recommendation would be to take everything but the vitamin B6 with a meal, as vitamins and minerals are usually best absorbed when taken with food. The B6, however, needs to be taken well apart from the levodopa, as you are doing. Bedtime is another good time to take B6. ._________________Best regards, Kathrynne Holden, MS -- For a Parkinson Tip of the Day visit: http://www.nutritionucanlivewith.com/
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Anonymous
Posted: Mon Sep 07, 2009 5:15 am Post subject:
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My vitamins namely : Riboflavin(Vit B2) 30mg ,Pantotheniv acid (vit.B5)30mg, Biotin (Vit H)m300mcg, Cyanocobalamin (Vit 12)200mcg, Vit C (TR) 1000mg,Thiamin (Vit B1)200mg,Niacinamide(Vit B3) 40 mg,Pyridoxin (Vit 6)50 mg, Zinc 70mg, Vit D3 2500 IU,fish oil(50%) 1000mg,Folic acid (Vit 9) 1200 mcg,Vit E (mixed natural) 200 IU, CoEnzyme Q10 200 mg
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Kathrynne Holden, MS
Joined: 22 Jan 2007
Posts: 94
Location: www.nutritionucanlivewith.com
Posted: Thu Sep 10, 2009 2:13 pm Post subject:
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Dear Friend,
50 mg of B6 is more than enough to interfere with levodopa absorption. Most people can take 10-15 mg, and some as much as 25 mg, without problem, but if PD symptoms are not well controlled it is likely that the amount is too much to be taken close to levodopa. If you're taking it singly, you might like to try taking all the other supplements with a meal, for best absorption, then taking the B6 about 2 hours separately from levodopa, or at bedtime.
.
_________________
Best regards,
Kathrynne Holden, MS
--
For a Parkinson Tip of the Day visit:
http://www.nutritionucanlivewith.com/
Anonymous
Posted: Thu Sep 17, 2009 8:38 am Post subject:
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I look better now by cutting down the supplement vitamins B6 from 50mg to 25mg daily two hours after the medication.
The overdose of vitamin B6 25mg two times a day at morning and evening caused the blockage of absorption of levodopa.
As the result I have frequent tiredness, facial stiffness and look sick, symptom of parkinson's.
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Kathrynne Holden, MS
Joined: 22 Jan 2007
Posts: 94
Location: www.nutritionucanlivewith.com
Posted: Fri Sep 18, 2009 6:58 am Post subject:
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Dear Friend,
I am very happy to hear that cutting back on the B6 is helping you to look and feel better. A total of 50 mg per day, taken in divided doses as you are doing, should be ample for your needs. And taking it two hours after your levodopa should provide plenty of time for the levodopa to be absorbed, so that the B6 does not block it.
Let me know if you have other questions in the future, and congratulations on solving this problem so successfully.
.
_________________
Best regards,
Kathrynne Holden, MS
--
For a Parkinson Tip of the Day visit:
http://www.nutritionucanlivewith.com/
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Anonymous
Posted: Sat Sep 19, 2009 9:58 pm Post subject:
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Kindly be informed I am taking Vit B6 25mg per day not 50mg as mentioned in your reply.
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Kathrynne Holden, MS
Joined: 22 Jan 2007
Posts: 94
Location: www.nutritionucanlivewith.com
Posted: Mon Sep 21, 2009 7:52 am Post subject:
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Dear Friend,
I misunderstood, thinking you were taking it twice daily. At any rate, 25 mg daily is approximately 4 times the daily requirement, and should be more than enough. And you have chosen to take it two hours after taking levodopa, which seems to correct your fatigue and other symptoms. Good for you for managing this problem so well.
.
_________________
Best regards,
Kathrynne Holden, MS
--
For a Parkinson Tip of the Day visit:
http://www.nutritionucanlivewith.com/
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