Saturday, March 10, 2012

parkinson disease

About Parkinson's Disease

Parkinson’s disease is a chronic, progressive neurological disease. It belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells. Dopamine, a neurochemical that controls communication between brain cells, is responsible for control of motor function. Nearly 80 percent of the dopamine producing cells in the brain die before the motor symptoms of Parkinson’s disease even appear. The four primary symptoms of Parkinson’s disease are tremor, or trembling in hands, arms, legs, jaw, and face; rigidity, or stiffness of the limbs and trunk; bradykinesia, or slowness of movement; and postural instability, or impaired balance and coordination. Other symptoms may include cognitive changes; difficulty in swallowing, chewing, and speaking; urinary problems or constipation; skin problems; and sleep disruptions. As these symptoms become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks. Early symptoms of Parkinson’s are subtle and occur gradually. In some people the disease progresses more quickly than in others.

Currently there is no cure, therapy, or drug to slow or halt the progression of Parkinson’s disease. While medication masks some symptoms for a limited period, generally four to eight years, dose-limiting side-effects do occur after time. Eventually the medications lose their effectiveness, leaving the person unable to move, speak or swallow.

In 1817, a British scientist named James Parkinson first described “the shaking palsy” in an essay. It was through this essay that he defined what we know as Parkinson’s disease today: “involuntary tremulous motion, with lessened muscular power, in parts not in action and even when supported; with a propensity to bend the trunk forwards, and to pass from a walking to a running pace: the senses and intellects being uninjured.”

It is unknown exactly how many Americans live with Parkinson’s disease, but most estimates range from 500,000 to 1.5 million. It is believed that nearly 60,000 people are diagnosed each year in the U.S. with Parkinson’s. The average age of diagnosis for Parkinson’s disease is 60 years old, but people as young as 18 have been diagnosed. Typically, anyone diagnosed under the age of 50 is considered as having young-onset Parkinson’s disease.

The cause of Parkinson’s disease remains unknown, but scientists and researchers believe there to be both genetic and environmental factors. In October 2003, scientists at NIH discovered that too much of the alpha-synuclein gene may cause Parkinson’s disease. More recently, scientists at the University of California at Los Angeles discovered that some pesticides used on plants and crops that end up in well water are linked to an increased risk of Parkinson’s disease. The environmental and genetic links to Parkinson’s disease are diverse, but the science continues to progress.

In order to establish better numbers and understanding about people with Parkinson’s, Congress has taken up a bill, H.R. 2595/S. 425, the National Neurological Diseases Surveillance System Act, that will create national, coordinated registries for both Parkinson’s disease and all neurological disorders. When the registry is implemented, we will learn important information about Parkinson’s disease such as geographic prevalence, disease clusters, and the number of Americans living with Parkinson’s disease.

PAN continues to fight for better treatments and a cure for Parkinson’s disease. Click here to learn more about PAN’s legislative priorities for the Parkinson’s disease community.


Parkinson's disease said...

Great information! We really appreciate the information published on one site.Thanks for Posting.

williamsmarkseo said...

I have being researching about parkinson disease and reading your blog, I found your post very helpful.

oakleyses said...

kate spade outlet, uggs on sale, ugg boots, burberry handbags, gucci handbags, oakley sunglasses wholesale, oakley sunglasses, burberry outlet, prada handbags, michael kors outlet online, polo ralph lauren outlet online, ugg boots, cheap oakley sunglasses, louis vuitton, nike outlet, tiffany jewelry, uggs outlet, christian louboutin shoes, longchamp outlet, oakley sunglasses, longchamp outlet, michael kors outlet online, ray ban sunglasses, prada outlet, longchamp outlet, ray ban sunglasses, louis vuitton, michael kors outlet, replica watches, louis vuitton outlet, nike air max, uggs outlet, ray ban sunglasses, replica watches, nike air max, jordan shoes, tory burch outlet, nike free, michael kors outlet online, tiffany and co, christian louboutin uk, chanel handbags, christian louboutin outlet, polo outlet, oakley sunglasses, louis vuitton outlet

oakleyses said...

vans pas cher, replica handbags, jordan pas cher, sac hermes, timberland pas cher, sac longchamp pas cher, nike roshe run uk, new balance, converse pas cher, burberry pas cher, guess pas cher, north face uk, hogan outlet, hollister uk, ralph lauren uk, michael kors pas cher, ray ban pas cher, true religion outlet, sac vanessa bruno, coach outlet store online, nike tn, air max, abercrombie and fitch uk, polo ralph lauren, polo lacoste, kate spade, coach outlet, nike air max uk, true religion outlet, nike air force, louboutin pas cher, michael kors, longchamp pas cher, nike blazer pas cher, michael kors, nike free uk, hollister pas cher, nike air max uk, north face, nike roshe, lululemon canada, true religion outlet, nike free run, oakley pas cher, mulberry uk, coach purses, true religion jeans, nike air max, michael kors outlet, ray ban uk

oakleyses said...

ferragamo shoes, iphone 6s cases, hollister, mac cosmetics, giuseppe zanotti outlet, babyliss, iphone 5s cases, ipad cases, ghd hair, nike trainers uk, celine handbags, hollister clothing, hermes belt, north face outlet, p90x workout, ralph lauren, wedding dresses, valentino shoes, iphone 6s plus cases, iphone 6 cases, timberland boots, herve leger, soccer shoes, asics running shoes, jimmy choo outlet, insanity workout, instyler, longchamp uk, new balance shoes, north face outlet, iphone 6 plus cases, nike huaraches, baseball bats, nike roshe run, iphone cases, louboutin, lululemon, bottega veneta, nfl jerseys, chi flat iron, s6 case, oakley, mcm handbags, beats by dre, vans outlet, reebok outlet, nike air max, soccer jerseys, abercrombie and fitch, mont blanc pens

oakleyses said...

doke gabbana, canada goose, moncler uk, toms shoes, converse, ugg uk, nike air max, doudoune moncler, canada goose jackets, canada goose outlet, moncler outlet, barbour, ray ban, links of london, hollister, ugg,uggs,uggs canada, ugg, thomas sabo, moncler, pandora jewelry, moncler, canada goose uk, karen millen uk, supra shoes, louis vuitton, moncler, louis vuitton, marc jacobs, converse outlet, louis vuitton, juicy couture outlet, replica watches, swarovski crystal, juicy couture outlet, louis vuitton, vans, gucci, ugg pas cher, pandora jewelry, canada goose, montre pas cher, moncler, wedding dresses, swarovski, canada goose outlet, hollister, barbour uk, moncler outlet, ugg,ugg australia,ugg italia, pandora charms, canada goose outlet, canada goose, pandora uk