Monday, October 4, 2010

parkinson and blood pressure

Posted: Fri Apr 18, 2008 6:13 am Post subject: Parkinson’s medication and Blood pressure

Dear Doctor, I am taking Lavodopa,Carbidopa and dopamin agonist for two year Close monitoring is required for people with certain medical condition. After I have a minor stroke (T.I.A) recently, I experience two different blood pressure i.e. decreased blood pressure when rising from a seated position or lie-down on bed after lengths of times. I feel dizziness on standing,headache or fainting My mouth run dry and thirsty Insomnia, anxiey, and fatigue, malaise Kindly elaborate Thanks TEOKIMHOE
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Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Sun Apr 20, 2008 7:05 pm Post subject:

There are many potential reasons for orthostasis or dizziness on standing up. Dopamine agonists and TCA antidepressants can have this as a side effect. Alternatively it could be an issue of hydration and you may need 6-8 glasses of water a day and compression stockings. Occassionally drugs like midodrine, florinef and mestinon are needed to keep the BP up._________________Michael S. Okun, M.D.
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Posted: Sun Apr 20, 2008 9:47 pm Post subject:

Normal blood pressure is regulated by specific reflexes in the nervous system. Parkinson’s disease can impair this reflex mechanism and result in lowered blood pressure.Low blood pressure usually presents itself as side-effect of anti parkinson’s medications. Levodopa-carbidopa, dopamine agonists and other antidepressions and sleeping medications may potentiate a hypotensive event Source: Linda P.Miller,R.N.Med Posted by Hero Teo at 10
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Posted: Sat Apr 26, 2008 2:16 am Post subject: dizzinness and parkinson’s medication

I am glad that your dizziness has subsided. Dizziness is a very common symptom among Parkinson’s patients. It needs extensive work-up, e.g. blood pressure, heart rhythm, blood tests (diabetes) and even brain scan. A common cause of dizziness among Parkinson’s patients is the medications for PD, which can lower the blood pressure. Commonly, I use fludrocortisone to elevate the blood pressure. Parkinson’s patients need regular blood pressure monitoring (lying position and standing). Dr Chew Nee Kong, Kuala Lumpur.
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Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Sun Apr 27, 2008 8:48 am Post subject:

Thanks for the nice comment._________________Michael S. Okun, M.D.

As dopamine agonists Ropinirole (Requip) can have this as a side effect (dizzinness at all time) I stop taking them i.e 6 mg Requip daily. I substitute Lavodopa 25/100 Sinemet 2 1/2 dosages with 2 dosage Jumax 5mg daily immediately.

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