Amantadine Side effects

Posted: Sat Feb 09, 2008 4:45 pm Post subject: Amantadine Side Effect

Dear Doctor, I am taking 3 Amantadine (100 mg), 2 Sinemet CR and 1 Sinemet 25/100, 12 Requip (2 mg) daily and to my surprise when added Amantadine recently it caused reddish mottling on few part of my body and legs which is sideeffect of Amantadine and I apply Antiseptic cream to stop itchiness. I have stopped the medicine. Kindly adivse
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Anonymous
Posted: Sun Feb 10, 2008 12:21 am Post subject: Amantadine Side effects

SIDE EFFECTS: This medication may cause stomach upset, nausea, drowsiness, constipation, headache, dizziness, anxiety, or purplish-red blotchy spots on the skin during the first few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor promptly. Notify your doctor if you develop: slurred speech, shortness of breath, swelling of the ankles/feet, unusual fatigue, vision disturbances, difficulty urinating, skin rash, mental/mood changes (sometimes severe, including rare thoughts of suicide), muscle stiffness, uncontrolled muscle movements, unusual sweating, fast heartbeat, unexplained fever. If you notice other effects not listed above, contact your doctor or pharmacist.
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Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Sun Feb 10, 2008 6:51 am Post subject:

Thank you for the question. This side effect is common (erythema nodosum) and may also be accompanied by edema or swelling. Usually if it is more than just a little mottling the dose or the drug is stopped. Hope that helps you and sorry you had a side effect._________________Michael S. Okun, M.D.
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Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Sun Feb 10, 2008 6:53 am Post subject:

Thank you for listing the side effects. To summarize in PD we mostly see swelling, rash, mottling and we don't give it to people with kidney problems. Occasionally it affects cognition or may result in hallucinations. It is generally well tolerated but one must always be vigilant._________________Michael S. Okun, M.D.
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Tue Feb 12, 2008 5:01 am Post subject: Side effects of Amantadine

I refer to my email. As Amantadine and Benzhexol are wonder drugs I continue the medication at lowest dosages i.e 1/2 dosage of Amantadine and Benxhexol (Artane) each two times daily. As they are new medication our body need times to adjust their side effects i.e dry mouth and skin rashes. My physical instructor amazes my achievement as my physical movement and mobilities are improved.




Joined: 20 Jan 2007Posts: 90
Posted: Tue Feb 12, 2008 4:09 pm Post subject:

I am glad these meds are working for you! Just remember that each person is different. What is good for you may not be so helpful for another patient. The good news is that we have much more options now that we did before. Yours,_________________Hubert H. Fernandez
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Dr. FernandezJoined: 20 Jan 2007Posts: 90
Posted: Tue Feb 12, 2008 4:14 pm Post subject:

Anything is possible...so yes, tasmar may cause it....BUT, this is not one of the typical side effects of tasmar...thus, to me it is unlikely. I would suggest you see a dermatologist for your rash....hard to tell what it is due without seeing it. But, although neurodermatitis can occur due to anxiety, to me it is also less likely...My guess is that this rash is due to something else...a dermatologist may clarify all these for you. Good luck!_________________Hubert H. Fernandez